Best antivirus to secure Office 365 [Virus Protection]

Milan Stanojevic
by Milan Stanojevic
Deputy Editor
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  • Office 365 benefits from built-in security in the form of Advanced Thread Protection (ATP).
  • If you want to up your security and endure your documents remain safe, you should use a third-party antivirus.
  • Check out the Microsoft Office Section for guides and tips so you can become a power user.
  • To learn more about keeping your business safe, visit our comprehensive Business Antivirus Section.
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Office 365 comes with antimalware and antispam protection as Microsoft introduced the world to the Advanced Threat Protection feature for Office 365.

Some of the benefits that came with this new solution include antimalware protection against known and unknown malware, real time protection against malicious links and URLs, as well as rich reporting and tracking capabilities for URLs.

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If you’re an Office 365 user with mailboxes hosted on the Microsoft Exchange Online, then your email messages, both incoming and outgoing are automatically protected from spam and malware.

Office 365 has a built-in antimalware and antispam filtering feature that protects inbound and outbound emails from malicious software and spam, plus administrators need not set up or maintain these filtering technologies as they’re enabled by default.

However, if you still feel the need for another antivirus for Office 365, there are a myriad of options you can choose from to suit your needs.

Antivirus software for Office 365:

BullGuard (recommended)

antivirus for Office 365

BullGuard antivirus for Office 365 incorporates innovative multi-layered defenses that block all forms of malicious threats, ensuring optimal performance.

Features include a vulnerability scanner to detect outdated software that is easily exploited by hackers, free and powerful backup to keep your files safe in case of a system crash or computer loss, behavioral-based detection, antispam filters, a feature that stops unwanted apps from hijacking your browser, and automatic PC tune-up.

With the traditional signature-based protection combined with behavioral-based protection, BullGuard protects against known and new malware outbreaks, with industry-leading detection rates.

It is simple to navigate with an effective, user-friendly design and easy to use dashboard interface with clearly marked features and actions. To learn more about how BullGuard works with Office and all the tools it uses to keep your system safe, check out our detailed BullGuard Internet Security review.



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Bitdefender (suggested)

antivirus for Office 365

Bitdefender is the leading antivirus for Office 365, which protects against any sophisticated threats, what with the GravityZone tool – adaptive, layered endpoint security designed for cloud and virtualization – that protects from advanced targeted attacks.

The GravityZone feature, found in Bitdefender GravityZone Business Security, executes its protective functions through its monitoring and revolutionary hypervisor introspection architecture, layered next-generation endpoint protection against cyber threats to detect advanced persistent threats, and protection from ransomware and defeats exploits, and zero-day attacks.

It is powerful, simple, and ideal for business use, plus it has consistently ranked first in independent tests.

You’ll find it easy to install and monitor remotely from a single, powerful cloud console, plus it is also very cost-effective.

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World's best antivirus
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  • Great price plan
  • VPN included
  • Best Windows compatibility
  • Awesome customer support

Emsisoft Anti-Malware

emsisoft anti-malware office 365

Emsisoft Anti-Malware is the perfect security extra-layer for your PC or laptop. It works perfectly on any hardware configuration and supports both x32 and x64 platforms.

This tool has a dual-engine scanner that keeps safe all your files and reacts instantly when a file has an unknown modification or source. Its anti-malware and anti-ransomware security will keep you safe while surfing. Another great feature is its Behaviour Blocker. This amazing tool detects even the not-yet-known threats and unknown signatures.

Emsisoft Anti-Malware is a great tool that comes at a great price, around $20, which is a better price than other popular antiviruses. It also has great rankings in many independent tests. You can find more information and download it in the link below.

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High performance antivirus
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  • Dual-engine Scanner
  • 4 protection layers to block online threats
  • Real time protection


antivirus for Office 365

Panda’s Cloud Protection is an antivirus for Office 365 that comes with endpoint cloud-based antimalware and firewall protection, plus email traffic filtering to assure that only virus and spam free emails reach your premises.

It also guarantees the highest protection for endpoints and emails, using its collective intelligence tool that ensures files are constantly and automatically updated.

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The firewall is personal or managed, plus it has cloud-based antispam filtering.

It is easy to use, minimal maintenance costs, and it optimizes the consumption of bandwidth and endpoint resources while avoiding inoperative traffic and minimizing server load.

Features include a hosted web console, profile-based protection, flexible installation, detailed email reports, vulnerability and threat assessment, plus management delegation among others.

For email protection, you get hosted email spam filtering, guaranteed availability, quarantine management, and unlimited domain alias, plus so much more.

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  • Real-time monitoring
  • Personal firewall
  • Device management
  • USB Protection

AVG Antivirus

avg antivirus antivirus for office 365Another solid antivirus software that you might want to consider is AVG Antivirus. This antivirus offers protection against standard threats including viruses, spyware, and ransomware. In addition, this tool will block unsafe links, downloads, and malicious email attachments.

The application also supports real-time security updates, and it can even scan your PC for performance problems. AVG Antivirus is available in two versions, and while the Free version has all aforementioned features, the Internet Security version offers complete system protection for your PC.

This version offers additional features such as an extra layer of ransomware protection and webcam protection. Another great feature available in this version is Enhanced Firewall, so you can easily monitor your online traffic and choose which applications have access to the Internet.

AVG Internet Security also has anti-phishing protection so it can easily detect malicious websites and prevent them from stealing your data. It’s worth mentioning that this tool is available on the Android platform as well, so if you need to protect your Android device, you might want to consider this tool.

Overall, AVG Antivirus offers solid features, and if you’re looking for basic protection, you might want to try the Free version. On the other hand, if you need full system protection along with some advanced features, you might want to consider getting Internet Security version.


  • Protection against malware, spyware, and ransomware
  • Anti-phishing detection
  • Extra ransomware protection
  • Webcam protection
  • Enhanced firewall

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Protects your PC forever
AVG Antivirus website logo
  • Block unsafe links, downloads, & email attachments
  • Stop viruses, spyware, ransomware
  • Real time-security updates


antivirus for Office 365

With Kaspersky Security antivirus for Office 365, you are able to protect your mailboxes managed through this cloud app. Your email messages are also scanned for viruses and other malware threats that may be transmitted via email, including spam and phishing.

Kaspersky Security for Microsoft Office 365 features antivirus, antiphishing and antispam protection, and attachment filtering.

It can scan incoming and outgoing mail for malware, filter spam from user mailboxes, scan email messages for phishing and malicious links, filter attachments in email messages, move messages to backup to prevent data loss risks, notify the system admin about messages with malicious objects or filtered attachments, and display app activity statistics.

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Essential for Windows
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  • Blocking ransomware, cryptolockers & more
  • Preventing cryptomining malware infections
  • Real-time protection

Norton by Symantec

antivirus for Office 365

This antivirus for Office 365 protects your sensitive data from loss or theft, protects user accounts, prevents threats in your emails, and blocks advanced attacks.

Besides, it allows you to respond quickly to security incidents with comprehensive log data.

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Most popular
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  • Backup and storage
  • Continuous malware scanning
  • Power Eraser (blocks suspicious files)

Are you ready to secure your business with any of these best antiviruses for Office 365? Share your favorite and why by leaving a comment in the section below.

FAQ: Office 365 Antivirus

  • Does Microsoft Office 365 include virus protection?

We’ve discussed what protection Office 365 has out of the box and what you can do to improve it in our Office security guide.

  • Is Office 365 ransomware safe?

If you have been hit by ransomware, you can restore backed-up files from the cloud. However, if you haven’t made copies of your documents, these decrypting tools might help you.

Editor’s Note: This post was originally published in January 2018 and has been since revamped and updated with new products so our users would have a wider range of alternatives.

Editor's Note: This article was originally published in January 2018 and was revamped and updated in October 2020 for freshness, accuracy, and comprehensiveness.