FIX: Failed to initialize connection subsystem in Cisco AnyConnect

Milan Stanojevic
by Milan Stanojevic
Deputy Editor
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Failed to initialize connection subsystem in Cisco AnyConnect

Cisco AnyConnect is more than just a virtual private network, as it empowers your workforce to be able to work from any location, on any device, and at any time. One such common problem is when you get the failed to initialize the connection subsystem in Cisco AnyConnect error, especially is using the Windows operating system.

This issue occurs when the following conditions hold true:

  • You run Cisco AnyConnect Secure Mobility Client app to establish VPN connections in Windows 8.1, RT 8.1, or Windows Server 2012 R2.
  • You installed Windows update 3023607 on your computer

Microsoft has confirmed that the failed to initialize connection subsystem in Cisco AnyConnect error is in Microsoft products such as Windows Server 2012 R2 Datacenter, Standard, Essentials and Foundation, Windows 8.1 Enterprise and Pro, Windows 8.1, and Windows RT 8.1.

Check out some solutions that can help you work around this error and resolve it on your computer.

Failed to initialize connection subsystem in Cisco AnyConnect error

  1. Go to Microsoft Update
  2. Run compatibility troubleshooter on Cisco AnyConnect
  3. Disable Internet Connection Sharing
  4. Edit the registry

1. Go to Microsoft Update

Microsoft Update will help you to install the most recent cumulative security update for Internet Explorer or Vulnerability in SChannel could allow security feature bypass: March 10, 2015 (MS15-031).

If you download and install updates manually, check the Affected Software table in Microsoft’s Security Bulletin MS15-018 for download links.

If this doesn’t help, try the next solution.

2. Run compatibility troubleshooter on Cisco AnyConnect

The failed to initialize connection subsystem in Cisco AnyConnect error usually has to do with a recent Windows Update, so you can run compatibility troubleshooter to resolve the issue by taking the steps below:

  1. Close Cisco AnyConnect Window and the taskbar mini-icon
  2. Go to the Cisco AnyConnect Secure Mobility Client folder – you can check in C:\Program Files (x86)\Cisco\Cisco AnyConnect Secure Mobility Client
  3. Right-click vpnui.exe
  4. Click Run compatibility troubleshooter
  5. Select Try recommended settings
  6. Select what the wizard suggests (Windows 8 compatibility)
  7. Click Test Program to open the program
  8. Close

Note: For vpnagent.exe – the local service that supports the client user interface – you may need to repeat these steps.

3. Disable Internet Connection Sharing

Sometimes the failed to initialize the connection subsystem in Cisco AnyConnect error could happen because the Internet Connection Sharing (ICS) is enabled on your LAN.

Here’s how to resolve this:

  1. Click on Start
  2. Select Settings
    failed to initialize connection subsystem in Cisco AnyConnect
  3. Click Network and Internet 
  4. In the search box, type Local
    failed to initialize connection subsystem in Cisco AnyConnect
  5. Select View Local Services
    failed to initialize connection subsystem in Cisco AnyConnect
  6. Right click on Internet Connection Sharing
    failed to initialize connection subsystem in Cisco AnyConnect
  7. Select Properties
    failed to initialize connection subsystem in Cisco AnyConnect
  8. Go to General tab
    failed to initialize connection subsystem in Cisco AnyConnect
  9. Go to Startup Type
    failed to initialize connection subsystem in Cisco AnyConnect
  10. Click the drop-down arrow and select Disabled
    failed to initialize connection subsystem in Cisco AnyConnect
  11. Click OK

 

 

 

 

 

 

 

 

4. Edit the registry

If you have the failed to initialize connection subsystem in Cisco AnyConnect error, you can fix it by making a small edit to the registry using the steps below:

  1. Right-click Start
  2. Select Run
    failed to initialize connection subsystem in Cisco AnyConnect
  3. Type regedit
  4. Press Enter
  5. Go to HKEY_CURRENT_USER\Software\Microsoft\Win
  6. Create a new key called GlobalOfflineUser
  7. Give it 1 as the value
  8. Restart your computer and load the VPN

 

Check whether you are able to connect.

Did any of these solutions fix the failed to initialize the connection subsystem in Cisco AnyConnect error for you? Let us know by dropping a comment in the section below.

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