4 best antivirus solutions for USB flash drives [2020 Guide]


Radu Tyrsina
by Radu Tyrsina
Founder & Editor-in-Chief
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Antivirus for USB flash drive

USB flash drives are useful storage devices that are not expensive at all. You can use a USB flash drive to keep emergency information and current project files always with you.

You can also use them to carry your browser and program settings with you and use them on any computer featuring a USB port. Flash drives are also useful for troubleshooting and repairing all kinds of issues.

You can also use a flash drive to make Windows run faster and run a different operating system without changing your hard drive.


Want to dual boot Windows 10 and another OS? Check out this guide to learn how you can properly do it.


USB flash drive makes life much easier. But wait a second! They can also pose a threat to your computer’s security.

If your USB flash drive is infected with malware, it can cause not only the loss of your data but also spread malware to all the computers it gets plugged into.

Today, the usage of USB drives has increased a lot because of their portability. Hackers, exploiters, and eavesdroppers have found many ways to use USB flash drive to infect PCs.

Infected USB flash drives can transfer personal or financial information to the intruder or even delete important data from your computer.

Prevention is always better than cure. For this reason, we’re going to the best tools to protect your computer against infected USB flash drives. We strongly recommend you use these tools.

What are the best antivirus software for flash drives?

Bitdefender USB Immunizer (recommended)

Autorun-based malware is one of the world’s most vicious e-threats. Introduced back in the Windows XP era, the Autorun feature has rapidly become the main infection tool for many cyber criminals.

The USB Immunizer software is Bitdefender’s response to this enormous and steadily growing problem. The software disables autorun-related threats before they can even access your computer.

Once the program is installed, it will regularly check for newly inserted USB storage devices, immunizing them on the spot.


If you need an antimalware solution, check out this list with our top picks.


If you plug in an infected USB drive, your computer will not auto-execute the malware code stored on it. The Computer Immunization setting disables the registry entry related to Autorun.

In this manner, a removable storage device (except for CD & DVD ROM media) won’t be able to execute any malware upon mounting. It also immunizes each system partition with a specially-crafted autorun.inf file.

The USB immunizer is available in English, Spanish, Portuguese, Arabic, Thai, Vietnamese, Polish, Farsi, German, French, and Romanian.

The software reads the current location of the user in the Region and Language settings and automatically loads the appropriate language file.

World's best antivirus
bitdefender 2019 product image
  • Great price plan
  • VPN included
  • Best Windows compatibility
  • Awesome customer support

Panda USB Vaccine (suggested)

The Panda USB vaccine is a free utility that disables the Autorun feature from USB drives, preventing malware from infecting your PC.

When this software is applied on the USB drive, it will permanently block the autorun.inf file and it will prevent it from being read, created, deleted and modified.


If you want to encrypt a USB flash drive on Windows 10, check out this article for the best tools to do that.


In this manner, Windows won’t be able to automatically execute any malicious file that might be stored on the flash drive.

You can then use your USB flash drive in a normal way to copy, move or delete files.

The software works great on FAT and FAT32 USB drives. As a quick reminder, the USB drives that have already been vaccinated can only be reversed to a previous state through formatting. Users can also operate the software via the command line.

We also recommend downloading Panda antivirus (50% off) which will double your USB-health security.

Recommended antivirus
panda dome
  • Real-time monitoring
  • Personal firewall
  • Device management
  • USB Protection

Editor’s Note: This article continues on the next page. If you’re interested in other antivirus software products, check out our wide collection of guides.