5+ best antiviruses with USB scanner for Windows 10/11

by Milan Stanojevic
Milan Stanojevic
Milan Stanojevic
Windows & Software Expert
Milan has been enthusiastic about PCs ever since his childhood days, and this led him to take interest in all PC-related technologies. Before joining WindowsReport, he worked as... read more
Affiliate Disclosure
  • You should use an antivirus with a USB scanner in order to protect your computer from malware coming on portable devices.
  • You can find in our list great freeware solutions from Avira and Avast, that will block any infected external storage.
  • A security tool that automatically scans and detects infected files on USB is the best choice.
  • Our top picks coming from ESET and Bitdefender include features as protection against spyware, viruses, worms, and more.
8 of the best antivirus with USB scanner for Windows 10
ESET Antivirus comes with all the security tools that you may ever need to protect your data and privacy, including:

  • Anti-theft support
  • Webcam protection
  • Intuitive setup and UI
  • Multi-platform support
  • Banking-level encryption
  • Low system requirements
  • Advanced anti-malware protection

An antivirus program needs to be fast, efficient, and cost-effective, and this one has them all.

Users who want to scan their USB flash drives for any malware or threats before opening the files therein may find an antivirus with USB scanner very handy.

With the USB scanner, you’re able to automatically scan any USB drive that is inserted into your computer or laptop with a simple click and see whether your USB is infected or not.

Here is the best antivirus with USB scanner compatible with Windows 10, that will protect your computer from viruses and other malware threats that can sneak in through a USB stick.

What is the best antivirus with USB scanner?

ESET Antivirus

antivirus with USB scanner

ESET Antivirus with USB scanner is designed to secure your USB drive using the USB DriveSecurity to protect your system and networks.

The award-winning ESET Antivirus engine detects and eliminates malware and other Internet threats before they’re transmitted onto your portable drives.

This means that any files on your USB are malware-free and safe to share with others. DriveSecurity operates from the USB drive itself so you don’t have to install anything on a host computer.

Now you can share files, play games, or even collaborate knowing your USB drives are safe. It is fast, convenient, and compatible with Windows.

You can also use public or shared computers knowing your drive and sensitive data on it is safe from any attempts to install spyware or worms.

ESET Antivirus

ESET Antivirus

ESET antivirus protects you across multiple platforms, and you can rest assured that your USBs are malware-free.

Free trialVisit website


router protection

Avira is another great choice if you are looking for a free antivirus solution for your PC. It is comprehensive, professional-level cybersecurity.

Avira protection will block all online threats you can think of, like malicious websites, ransomware, and any spyware that you can get while surfing the Internet.

As per the USB flash drives or other media storage connected to your computer, the antivirus will block any infected device. So, you don’t have to worry when using a USB with documents from another PC.



Use a comprehensive cybersecurity solution that will scan and block infected USB devices.


This antivirus with USB scanner comes with the Panda USB vaccine, a free antimalware to block malware spreading to your computer through USB flash drives.

There is an increasing number of viruses that spread via USB flash drives and other removable devices like memory sticks, digital cameras, and other devices.

Panda’s USB Vaccine offers a double layer of preventive protection that allows you to disable the autorun feature on computers as well as USB drives.

USB Vaccine disables the autorun file so it cannot be read, modified, or replaced by malicious code. It is a useful tool that offers a high degree of protection against infections from removable devices.

When applied to a USB drive, it will permanently block the innocuous autorun.inf file, preventing it from any action that may modify it, but, you can use the drive normally by copying files to and from it.

However, files will be prevented from opening automatically.



Use an antivirus with great device management, USB protection and real time monitoring.

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An infected USB drive can ruin your computer when it is inserted without being scanned for any threats.

In order to protect your computer from the dangers of viruses and malware, you need to have an antivirus with a USB scanner.

Kaspersky PURE comes with three scanning options: Quick scan, Full scan, or Do not scan.

To configure the automatic scan of USB drives upon insertion, click Settings and select General Settings in the Scan section.

In the Scan removal drives on connection section, select either quick scan, full scan, or Do not scan options, the latter which will not scan removable drives on their connection.

You can also specify the maximum drive size to scan. It is compatible with Windows platforms, Mac and mobile devices as well.



Use an antivirus with real-time protection against malware infections and ransomware from USB.

Free trialVisit website


Sophos antivirus with USB scanner is useful for scanning removable devices as it detects devices upon insertion, and when you access a file.

Sophos antivirus runs an on-access scan subject to the configuration you set up on your computer. You can also set up an on-demand scan and select the removable device you want scanning.

If you want to run an additional scan when you insert a USB drive, you can right click on the USB drive, and then select Scan with Sophos antivirus.



Use an antivirus with artificial intelligence threat detection that scans removable devices automatically when you insert them.

Free trialVisit website

Bitdefender USB Immunizer

This leading, powerful antivirus created the USB immunizer as a response to the growing malware issues, especially the autorun-based malware, which has been a nuisance e-threat globally.

Some of the autorun-based malware that have troubled USB drive users for years include the Trojan.AutorunInf, the Conficker worm, and/or Worm.Autorun.VHD.

Bitdefender introduced the USB immunizer becoming one of the antiviruses with USB scanner with powerful action against malware detected once USB drives are inserted into a computer.

The USB immunizer disables threats before they access the computer and once installed, it constantly monitors and watches for newly inserted USB devices and immunizes them on the fly.

In the event that you plug in an infected USB drive accidentally, and it hasn’t been immunized, your computer won’t auto-execute the malware located in the USB device.

You can immunize a USB device as soon as it is plugged into the computer if you have the USB immunizer running, by ticking the automatically immunize USB drives box under the Options tab.

Each non-immunized USB drive plugged into your computer will be automatically immunized.

However, the USB immunizer only lists removable media as they are most prone to infections such as the autorun.inf type.

Get Bitdefender USB Immunizer

Avast Free Antivirus

Whenever you plug an unknown USB drive into your computer, you’re risking your system because malware can spread or get into the drive itself.

Avast Free Antivirus with USB scanner has pre-defined scans installed such as the ability to scan any USB device connected to your computer.

It will detect potential auto-run programs that may try to launch when the drive is inserted. Avast Free Antivirus checks every file to determine its type and whether it should be scanned.

If you want to carry out a manual scan of USB drives instead, you need to select the Scan tab which will open the Scan screen.

The Quick scan option performs a scan of the C drive which usually detects the majority of malware found in files with dangerous extensions.

While a full system scan performs a detailed scan of all your computer’s hard disks and finds any possible infected programs, files, etc.

Get Avast Free Antivirus

Trend Micro


Trend Micro antivirus with USB scanner features real time virus scan with its USB Security tool so that if a threat is detected, an alert screen displays and the infected files are isolated immediately.

USB Security also auto-updates on pattern files owing to the dynamic nature of threats, and automatically updates its pattern files, though you can also get manual updates.

It also keeps an interactive reference log of virus detection results where you can restore or delete any file on the quarantine list.

When it detects a virus, it cleans the infected file(s), but if the clean fails, the file(s) is automatically quarantined and you get a notification about it.

Get Trend Micro USB Security


BullGuard antivirus scans portable drives like USB drives for threats or malware that may be attached to files being transferred to your computer from the drive, which can spread infections.

Through its USB detector, BullGuard detects and scans USB flash drives for any threats or malware immediately they are inserted into the USB ports.

Users who share files often using USB drives may need to use this antivirus with USB scanner as it offers more than just protection for your USB.

You can also enjoy their amazing customer service and extra level protection to your computer from contracting any malware or viruses.

Get Bullguard

If you want to discover more software to protect your computer, check our guide including the best lifetime license antivirus tools.

Which antivirus with USB scanner do you use? Did it make the list? Share with us your favorite, and your experience with it in the comments section below.

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